Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: Potential therapy for postoperative pulmonary hypertension
The Journal of Thoracic and Cardiovascular Surgery, ISSN: 0022-5223, Vol: 134, Issue: 2, Page: 319-326
2007
- 63Citations
- 48Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations63
- Citation Indexes61
- 61
- CrossRef54
- Patent Family Citations2
- Patent Families2
- Captures48
- Readers48
- 48
Article Description
Pulmonary hypertension may complicate surgical correction of congenital heart defects, resulting in increased morbidity and mortality. We have previously shown that plasma levels of the nitric oxide precursors citrulline and arginine drop precipitously after congenital cardiac surgery and that oral citrulline supplementation may be protective against the development of pulmonary hypertension. In this study, we assessed the safety and pharmacokinetic profile of intravenous citrulline as a potential therapy for postoperative pulmonary hypertension.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0022522307006162; http://dx.doi.org/10.1016/j.jtcvs.2007.02.043; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34447617341&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/17662768; https://linkinghub.elsevier.com/retrieve/pii/S0022522307006162; https://dx.doi.org/10.1016/j.jtcvs.2007.02.043
Elsevier BV
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