Efecto de la duración del decúbito prono en pacientes con SDRA durante la pandemia por SARS-CoV-2
Medicina Intensiva, ISSN: 0210-5691, Vol: 47, Issue: 10, Page: 575-582
2023
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Article Description
Describir las características de los pacientes con síndrome de distrés respiratorio agudo por neumonía bilateral por COVID-19 en ventilación mecánica invasiva (VMI) y analizar el efecto del decúbito prono prolongado > 24 h (DPP) respecto al decúbito prono < 24 h (DP). Estudio observacional retrospectivo descriptivo. Análisis uni y bivariante. Servicio de Medicina Intensiva del Hospital General Universitario de Elche. Pacientes con neumonía por SARS-CoV-2 (2020-2021) en VMI por síndrome de distrés respiratorio agudo moderado-severo. VMI. Maniobras de DP. Sociodemográficas; analgosedación; bloqueo neuromuscular; DP (duración), estancia y mortalidad en UCI, días de VMI; complicaciones no infecciosas; infecciones asociadas a la asistencia sanitaria. Cincuenta y un pacientes precisaron DP y de ellos 31 (69,78%) requirieron DPP. No se encontraron diferencias en las características iniciales de los pacientes (sexo, edad, comorbilidades, gravedad inicial, o en el tratamiento antiviral y antiinflamatorio recibido). Los pacientes con DPP presentaron menor tolerancia a la ventilación en decúbito supino (61,29 vs. 89,47%, p = 0,031), mayor estancia hospitalaria (41 vs. 30 días, p = 0,023), más días de VMI (32 vs. 20 días, p = 0,032), mayor duración del tratamiento con bloqueo neuromuscular (10,5 vs. 3 días, p = 0,0002), así como un mayor porcentaje de episodios de obstrucción del tubo orotraqueal (48,39 vs. 15%, p = 0,014). El DPP se asoció con mayor uso de recursos y complicaciones en pacientes con síndrome de distrés respiratorio agudo moderado-severo por COVID-19. To describe the characteristics of patients with acute respiratory distress syndrome due to bilateral COVID-19 pneumonia on invasive mechanical ventilation (IMV) and analyze the effect of prolonged prone decubitus > 24 h (PPD) compared to prone decubitus < 24 h (PD). Retrospective observational descriptive study. Uni and bivariate analysis. Department of Intensive Care Medicine. General University Hospital of Elche. Patients with SARS-CoV-2 pneumonia (2020–2021) in VMI for moderate-severe acute respiratory distress syndrome, ventilated in PD. IMV. PD maneuvers. Sociodemographic; analgo-sedation; neuromuscular blockade; PD (duration), ICU stay and mortality, days of IMV; non-infectious complications; health care-associated infections. Fifty-one patients required PD and of these 31 (69.78%) required PPD. No differences were found in patient characteristics (sex, age, comorbidities, initial severity, antiviral and anti-inflammatory treatment received). Patients on PPD had lower tolerance to supine ventilation (61.29 vs. 89.47%, p = 0.031), longer hospital stay (41 vs. 30 days, p = 0.023), more days of IMV (32 vs. 20 days, p = 0.032), longer duration of neuromuscular blockade (10.5 vs. 3 days, p = 0.0002), as well as a higher percentage of episodes of orotracheal tube obstruction (48.39 vs. 15%, p = 0.014). PPD was associated with higher resource use and complications in patients with moderate-severe acute respiratory distress syndrome by COVID-19.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0210569123000591; http://dx.doi.org/10.1016/j.medin.2023.03.002; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85152253900&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/37359240; https://linkinghub.elsevier.com/retrieve/pii/S0210569123000591; https://dx.doi.org/10.1016/j.medin.2023.03.002
Elsevier BV
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