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Regioselective synthesis of 2-(1 H -benzimidazol-1-yl)-5-nitro- and 2-(5-nitro-1 H -benzimidazol-1-yl)anilines

Mendeleev Communications, ISSN: 0959-9436, Vol: 33, Issue: 5, Page: 650-652
2023
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Article Description

The efficiency of two strategies for the synthesis of N -(2-aminophenyl)-5-nitrobenzimidazole derivatives was studied. The promising route involves the stages of 1-(2,4-dinitro-phenyl)-1 H -benzimidazole monoreduction at 2-positioned nitro group and tandem conversion involving recyclization of the intermediate N -(2-amino-4-nitrophenyl)-5-nitrobenz-imidazole.

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