Near-infrared spectroscopy as a feasible method for the differentiation of Neisseria gonorrhoeae from Neisseria commensals and antimicrobial resistant from susceptible gonococcal strains
Journal of Microbiological Methods, ISSN: 0167-7012, Vol: 201, Page: 106576
2022
- 1Citations
- 10Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations1
- Citation Indexes1
- Captures10
- Readers10
- 10
Article Description
Rapid and cost-effective diagnosis of Neisseria gonorrhoeae (NG) are important measures for the control and management of gonococcal infection. Current diagnostic tools such as nucleic acid amplification tests and bacterial culture are not feasible in many resource-poor settings, and so syndromic patient management is commonplace. Alternative cost-effective diagnostic tools are therefore needed. Here, we sought to explore the utility and feasibility of Near Infrared Spectroscopy (NIRS) to (1) identify and differentiate NG from Neisseria c ommensals and (2) to differentiate fully susceptible NG from resistant NG. NIRS correctly classified NG from Neisseria commensals (R 2 = 0.89; SECV 0.164) and to a lesser capacity, susceptible NG from resistant (R 2 = 0.60; SECV 0.32). To the best our knowledge, this is the first proof of concept study in the field. Further evaluations are now warranted to enhance capacity and accuracy of this diagnostic approach.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0167701222001713; http://dx.doi.org/10.1016/j.mimet.2022.106576; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85139571303&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/36096277; https://linkinghub.elsevier.com/retrieve/pii/S0167701222001713; https://dx.doi.org/10.1016/j.mimet.2022.106576
Elsevier BV
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