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Peculiarities of some Fmoc-dipeptides gelation in DMSO/water medium

Journal of Molecular Liquids, ISSN: 0167-7322, Vol: 387, Page: 122613
2023
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Article Description

The possibility of the gels formation with a high-water content of 90% v/v using Fmoc-dipeptides without mechanical actions or pH-switching was demonstrated. For the first time, the formation of a colloid gel based on Fmoc-LL dipeptide was discovered. The effect of side substituents in the amino acid residues of Fmoc-dipeptides in the range of GG, AA, LL, and FF on their ability to form gels in DMSO/water systems was thoroughly studied. Non-linear dependence of gel formation kinetics in dipeptide/DMSO/water systems, gel properties, and supramolecular organization in xerogels on the size of side substituents was observed. The results obtained give a new insight into the mechanism of gelation with low-molecular-weight gelators based on Fmoc-dipeptides and may be useful for the preparation of new supramolecular or colloidal gels.

Bibliographic Details

Shamil R. Akhmetshin; Radik A. Larionov; Alexander E. Klimovitskii; Polina V. Skvortsova; Aydar A. Akhmadiyarov; Sufia A. Ziganshina; Valery A. Gorbatchuk; Marat A. Ziganshin

Elsevier BV

Materials Science; Physics and Astronomy; Chemistry

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