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Infections in the immunocompromised host: primary immunodeficiency disorders

Medicine, ISSN: 1357-3039, Vol: 49, Issue: 10, Page: 603-610
2021
  • 2
    Citations
  • 0
    Usage
  • 20
    Captures
  • 0
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    2
    • Citation Indexes
      2
  • Captures
    20
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Review Description

The primary immunodeficiency disorders (PIDs) are clinically heterogeneous diseases that frequently arise from inborn errors in immunologically relevant genes and present with recurrent infections. A high index of suspicion is required to reach a diagnosis of primary immunodeficiency, and a timely diagnosis significantly improves patient outcomes. This contribution reviews the relationships between the molecular defects associated with PID, the susceptibility to infections these defects confer and diagnostic and therapeutic approaches.

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