Sensory function and quality of life in patients with multiple sclerosis and pain
Pain, ISSN: 0304-3959, Vol: 114, Issue: 3, Page: 473-481
2005
- 176Citations
- 172Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations176
- Citation Indexes173
- 173
- CrossRef120
- Policy Citations2
- Policy Citation2
- Patent Family Citations1
- Patent Families1
- Captures172
- Readers172
- 172
Article Description
Central neuropathic pain is well known in multiple sclerosis (MS), but the underlying mechanisms are unclear. In the present study we studied sensory function in MS patients with pain, MS patients without pain and healthy subjects in order to clarify the role of sensory abnormalities in pain. Fifty MS patients with pain were randomly recruited from a previous epidemiological MS study in Aarhus County, Denmark. Age and gender stratified MS patients without pain ( N =50) and healthy subjects ( N =50) served as controls. Patients with pain underwent a structured pain interview. Sensory function was examined by bedside and quantitative sensory testing. Quality of life was assessed using the health-related quality of life questionnaire, SF-36. Patients with pain had lower pressure pain threshold than pain-free patients (260 kPa vs. 322 (median), P =0.02) otherwise quantitative sensory testing was similar. Pain patients more frequently had cold allodynia (9/50 vs. 0/50, P =0.003) and abnormal temporal summation (10/48 vs. 3/49, P =0.03). Fifty-eight percent had central pain. Central pain patients did not differ from musculoskeletal pain patients in quantitative sensory testing, but allodynia was more common in MS patients with central pain. Pain patients scored lower in all dimensions of SF-36 compared with pain-free patients and healthy subjects. The results suggest that pain in MS is central in more than half of the patients and is associated with mechanical or thermal hyperalgesia.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0304395905000217; http://dx.doi.org/10.1016/j.pain.2005.01.015; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=15244350642&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/15777872; https://journals.lww.com/00006396-200504000-00019; https://dx.doi.org/10.1016/j.pain.2005.01.015; https://insights.ovid.com/article/00006396-200504000-00019
Ovid Technologies (Wolters Kluwer Health)
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