Bioassay-guided isolation of antifungal cyclopeptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020
Phytochemistry Letters, ISSN: 1874-3900, Vol: 48, Page: 68-71
2022
- 9Citations
- 6Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
Two new cyclopeptides simplicilliumtides N and O ( 1 and 2 ) along with three known analogues verlamelins A, B and simplicilliumtide J ( 3-5 ) were isolated from the deep-sea-derived fungal strain Simplicillium obclavatum EIODSF 020 by bioassay-guided isolation method. Their structures of 1 and 2 were elucidated by spectroscopic analysis, and their amino acid configurations were determined by Marfey’s method. All isolated compounds showed significant antifungal activity against two phytopathogenic fungi Alternaria solani and Colletotricum asianum with MIC values of 0.195–6.250 μg/disc. This study suggests the fungal strain S. obclavatum EIODSF 020 is a new source for developing natural fungicides.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1874390022000283; http://dx.doi.org/10.1016/j.phytol.2022.01.017; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85124392000&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S1874390022000283; https://dx.doi.org/10.1016/j.phytol.2022.01.017
Elsevier BV
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