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Rhizomes of Rumex abyssinicus Jacq.: Unveiling five new anthraquinones (Rumabynosides A-E) and a review on hepatoprotective potential of its phytochemicals

Phytochemistry Letters, ISSN: 1874-3900, Vol: 64, Page: 30-36
2024
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Study Data from University of Dschang Provide New Insights into Phytochemistry [Rhizomes of Rumex Abyssinicus Jacq.: Unveiling Five New Anthraquinones (Rumabynosides A-e) and a Review On Hepatoprotective Potential of Its Phytochemicals]

2024 NOV 28 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Daily -- New research on Chemistry - Phytochemistry is the

Article Description

Five hitherto unreported anthraquinone glycoside derivatives, rumabynosides A–E ( 1–5 ), along with twenty previously reported compounds, were isolated from the rhizomes of Rumex abyssinicus. Three of these new anthraquinones carried an uncommon substituent (3-hydroxy-3-methylglutaroyl) attached to the sugar moiety. Their structures were elucidated by comprehensive UV, IR, HRESIMS, 1D NMR ( 1 H and 13 C NMR) and 2D NMR (HSQC, COSY, HMBC, NOESY) analyses. A literature survey revealed hepatoprotective activities of some of the isolated compounds, thus adding weight to the wide use of this plant against various liver diseases in traditional medicine.

Bibliographic Details

Leopoldine T. Lonkeng; Paul Eckhardt; Borice.T. Tsafack; Robert Forster; Beaudelaire K. Ponou; Rémy B. Teponno; Télesphore B. Nguelefack; Till Opatz; Léon A. Tapondjou

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences

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