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Salicylic acid and methyl jasmonate but not Rose Bengal enhance artemisinin production through invoking burst of endogenous singlet oxygen

Plant Science, ISSN: 0168-9452, Vol: 178, Issue: 4, Page: 390-397
2010
  • 56
    Citations
  • 0
    Usage
  • 40
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    56
    • Citation Indexes
      56
  • Captures
    40

Article Description

As a cis element responsive to oxidative stresses, the promoter of amorphadiene synthase gene ( pADS ) from Artemisia annua was also found to be inducible by salicylic acid (SA) and methyl jasmonate (MJ), which had been evident by phenotyping pADS -driven β-glucuronidase reporter gene ( GUS ) in transgenic Nicotiana tabacum incubated with SA/MJ. Furthermore, SA/MJ-treated A. annua exhibited a correlation of the up-regulation of ADS gene with the emission of singlet oxygen ( 1 O 2 ), suggesting that SA/MJ induced artemisinin overproduction through invoking 1 O 2 burst. Supplement with Rose Bengal (RB), a photosensitizing 1 O 2 generator, or direct exposure to a 1 O 2 -generating pool, however, failed to facilitate artemisinin accumulation in subjected A. annua. Alteration of metabolite profiles and fluctuation of H 2 O 2 level suggested that RB treatment might have led to a diminished endogenous 1 O 2 release from A. annua, thereby reiterating an important role of the endogenous 1 O 2 rather than the exogenous 1 O 2 in enhanced artemisinin production.

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