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GhMYC1374 regulates the cotton defense response to cotton aphids by mediating the production of flavonoids and free gossypol

Plant Physiology and Biochemistry, ISSN: 0981-9428, Vol: 205, Page: 108162
2023
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Article Description

Myelocytomatosis (MYC) transcription factors (TFs) in plants are well-known regulators of plant defense against herbivores. However, the role and mechanism of MYC TFs in cotton ( Gossypium hirsutum L.) defense against cotton aphids ( Aphis gossypii Glover) remain still elusive. Herein, on the basis of aphid-induced cotton transcriptome analysis, GhMYC1374, a cotton MYC2-like TF that was highly induced by cotton aphid attack, has been identified that confers cotton aphid resistance in cotton. GhMYC1374 was an intranuclear transcription factor with three domains: bHLH-MYC_N, RBR and bHLH_AtAIB_like. GhMYC137 4 was induced under cotton aphid feeding, exogenous methyl jasmonate (MeJA) and salicylic acid (SA) treatments. GhMYC1374 transient overexpression in cotton plants enhanced cotton aphid-resistance, while GhMYC1374 silence through VIGS (virus induced gene silencing) decreased cotton aphid-resistance. GhMYC1374 transient overexpression of in cotton plants activated the phenylpropane pathway and promoted the synthesis of flavonoids, and resistance to thus enhanced the cotton resistance against aphids. In contrast, GhMYC1374 silence inhibited the biosynthesis of flavonoids. In addition, GhMYC1374 also positively activated the expression of the biosynthetic genes of free gossypol, leading to the high content of free gossypol. Taken together, our results suggest that GhMYC1374 is involved in the cotton defense response against cotton aphids by regulating the biosynthesis of flavonoids and free gossypol.

Bibliographic Details

Zhang, Yi; Wang, Yuxue; Liu, Ting; Luo, Xincheng; Wang, Yi; Chu, Longyan; Li, Jianpin; An, Hongliu; Wan, Peng; Xu, Dong; Yang, Yazhen; Zhang, Jianmin

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences

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