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PTEN regulation in virus-associated cancers

Pathology - Research and Practice, ISSN: 0344-0338, Vol: 266, Page: 155749
2025
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Review Description

Despite advancements in science, researchers still face challenges in curing patients with malignancies. This health issue is linked to various risk factors, including alcohol consumption, age, sex, and infectious diseases. Among these, viral agents play a significant role in cancer-related health problems and are currently a subject of ongoing research. In this review, we summarize how several viruses—such as herpesviruses, human papillomavirus, hepatitis B virus, hepatitis C virus, and adenovirus—impact cancer signaling pathways through their effects on the tumor suppressor PTEN.

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