PlumX Metrics
Embed PlumX Metrics

The price of seizure control: Dynorphins in interictal and postictal psychosis

Psychiatry Research, ISSN: 0165-1781, Vol: 151, Issue: 1, Page: 139-143
2007
  • 22
    Citations
  • 0
    Usage
  • 16
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Review Description

Postictal and interictal psychoses are relatively common complicating factors in the clinical course of epilepsy, yet their neurobiological substrates are poorly understood. Recent evidence shows that kappa opioid receptor (KOR) activation elicits anticonvulsant and psychotomimetic effects. In view of this background, here we introduce the hypothesis that epilepsy-related psychoses may partially result from excessive hippocampal dynorphin release and kappa opioid receptor overstimulation aimed at seizure control.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know