Parasite interaction with host complement: beyond attack regulation
Trends in Parasitology, ISSN: 1471-4922, Vol: 20, Issue: 9, Page: 407-412
2004
- 12Citations
- 36Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations12
- Citation Indexes12
- 12
- CrossRef11
- Captures36
- Readers36
- 36
Article Description
Many orthologous proteins of known mammalian receptors have been discovered in parasites. Besides disguising the parasite as self in terms of the host immune system, evidence is accumulating that these receptors link to signalling pathways in parasites that appear to be involved in their growth or development. Recently, several proteins of the host complement system, which forms part of the innate defence against invading microorganisms, have been shown to possess alternative functions. These complement proteins interact with signalling pathways involved in early development and differentiation, as well as organ and tissue regeneration. By altering cellular interactions and responses, complement is being shown to have novel roles besides the originally described inflammatory role. The possibility exists that, as for other host factors interacting with parasites and affecting their growth or development, host complement proteins could also have such an influence.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1471492204001746; http://dx.doi.org/10.1016/j.pt.2004.07.001; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=6044240485&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/15324730; https://linkinghub.elsevier.com/retrieve/pii/S1471492204001746; https://dx.doi.org/10.1016/j.pt.2004.07.001
Elsevier BV
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