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Reporter parasite lines: valuable tools for the study of Plasmodium biology

Trends in Parasitology, ISSN: 1471-4922, Vol: 40, Issue: 11, Page: 1000-1015
2024
  • 0
    Citations
  • 0
    Usage
  • 10
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Captures
    10
  • Mentions
    1
    • News Mentions
      1
      • 1

Most Recent News

Study Results from Nagasaki University Provide New Insights into Malaria (Reporter Parasite Lines: Valuable Tools for the Study of Plasmodium Biology)

2024 DEC 10 (NewsRx) -- By a News Reporter-Staff News Editor at Zika & Mosquito Daily -- Fresh data on Mosquito-Borne Diseases - Malaria are

Review Description

The human malaria parasite Plasmodium falciparum causes the most severe form of malaria in endemic regions and is transmitted via mosquito bites. To better understand the biology of this deadly pathogen, a variety of P. falciparum reporter lines have been generated using transgenic approaches to express reporter proteins, such as fluorescent proteins and luciferases. This review discusses the advances in recently generated P. falciparum transgenic reporter lines, which will aid in the investigation of parasite physiology and the discovery of novel antimalarial drugs. Future prospects for the generation of new and superior human malaria parasite reporter lines are also discussed, and unresolved questions in malaria biology are highlighted to help boost support for the development and implementation of malaria treatments.

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