Molecular properties and regulation of NAD + kinase (NADK)
Redox Biology, ISSN: 2213-2317, Vol: 59, Page: 102561
2023
- 34Citations
- 27Captures
- 1Mentions
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Metrics Details
- Citations34
- Citation Indexes34
- 34
- Captures27
- Readers27
- 27
- Mentions1
- News Mentions1
- News1
Most Recent News
Research from Rutgers University - The State University of New Jersey Has Provided New Data on Biology [Molecular properties and regulation of NAD+ kinase (NADK)]
2023 FEB 07 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Life Science Daily -- Data detailed on biology have been presented. According
Review Description
Nicotinamide adenine dinucleotide (NAD + ) kinase (NADK) phosphorylates NAD +, thereby producing nicotinamide adenine dinucleotide phosphate (NADP). Both NADK genes and the NADP(H)-producing mechanism are evolutionarily conserved among archaea, bacteria, plants and mammals. In mammals, NADK is activated by phosphorylation and protein-protein interaction. Recent studies conducted using genetically altered models validate the essential role of NADK in cellular redox homeostasis and metabolism in multicellular organisms. Here, we describe the evolutionary conservation, molecular properties, and signaling mechanisms and discuss the pathophysiological significance of NADK.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2213231722003330; http://dx.doi.org/10.1016/j.redox.2022.102561; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85143721674&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/36512915; https://linkinghub.elsevier.com/retrieve/pii/S2213231722003330; https://dx.doi.org/10.1016/j.redox.2022.102561
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