Comparison of the influence of two different constant-rate infusions (dexmedetomidine versus morphine) on anaesthetic requirements, cardiopulmonary function and recovery quality in isoflurane anaesthetized horses
Research in Veterinary Science, ISSN: 0034-5288, Vol: 95, Issue: 3, Page: 1186-1194
2013
- 39Citations
- 62Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations39
- Citation Indexes39
- 39
- CrossRef31
- Captures62
- Readers62
- 62
Article Description
Twenty adult healthy horses undergoing elective surgery were involved in this prospective, blinded, clinical study. Horses were randomly allocated to receive a constant rate infusion (CRI) of morphine or dexmedetomidine. After induction, anaesthesia was maintained with isoflurane in oxygen/air and mechanical ventilation applied. The end-tidal isoflurane concentration (F E ́ISO) was initially set at 0.9% and adjusted by the anaesthetist, to maintain a light surgical plane of anaesthesia, according to an objective flow-chart. The cardiopulmonary function was only minimally different between groups and maintained within clinically normal ranges. Less ketamine was required, F E ́ISO was lower after 1 h and fewer alterations in the anaesthetic depth were needed in horses receiving dexmedetomidine, with better recoveries. One horse receiving morphine developed post-operative colic and pulmonary oedema and two showed box-walking behaviour. This study showed that a dexmedetomidine CRI produced a more stable anaesthetic depth, reduced isoflurane requirements and better recoveries, without post-operative complications compared with a morphine CRI.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0034528813003147; http://dx.doi.org/10.1016/j.rvsc.2013.09.014; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84888005772&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/24148870; https://linkinghub.elsevier.com/retrieve/pii/S0034528813003147; https://dx.doi.org/10.1016/j.rvsc.2013.09.014
Elsevier BV
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