Off-label: The results of adjunctive bone morphogenetic protein for challenging femur fractures; a review of two cases
Trauma Case Reports, ISSN: 2352-6440, Vol: 50, Page: 100979
2024
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
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Case Description
Although bone morphogenetic proteins (BMPs) are used as an adjunct to promote healing, they may have unintended effects such as heterotopic ossification (HO). The literature is limited regarding the effect of using off-label BMPs for femur fractures. We report two outcomes after off-label use of BMPs for the treatment of femur fractures and propose a possible explanation for the difference. BMPs are critical osteoinductive factors in injured bone and muscle that facilitate bony healing. However, it may be important to recognize the potentially negative effects of adding BMP to bone graft material in certain cases to stimulate bone repair. We hope this case series helps surgeons consider the risks and benefits of using BMP for femur fractures, and therefore to decide with caution when BMP is indicated.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2352644024000025; http://dx.doi.org/10.1016/j.tcr.2024.100979; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85184489678&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/38357291; https://linkinghub.elsevier.com/retrieve/pii/S2352644024000025; https://dx.doi.org/10.1016/j.tcr.2024.100979
Elsevier BV
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