Hashimoto's thyroiditis and papillary thyroid cancer: are they immunologically linked?
Trends in Endocrinology & Metabolism, ISSN: 1043-2760, Vol: 25, Issue: 12, Page: 656-664
2014
- 103Citations
- 110Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations103
- Citation Indexes103
- 103
- CrossRef83
- Captures110
- Readers110
- 109
Review Description
Hashimoto's thyroiditis (HT) is the most common autoimmune disease in humans frequently leading to hypothyroidism. HT is characterized by a cellular immune response with lymphatic infiltration of the thyroid gland by T and B cells, as well as by a humoral immune response leading to specific antibody production. The synchronous appearance of HT and papillary thyroid cancer (PTC) indicates an immunological link between the two entities. Three different pathomechanisms may be postulated, including preexisting autoimmunity leading to malignancy due to inflammation, immunity towards preexisiting tumor cells leading to specific autoimmunity, and immune tolerance leading to malignancy despite (auto)immunity. In this article we review data describing these potential mechanisms that might lead to the synchronous appearance of HT and PTC.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S104327601400160X; http://dx.doi.org/10.1016/j.tem.2014.09.001; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84922905988&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/25306886; https://linkinghub.elsevier.com/retrieve/pii/S104327601400160X
Elsevier BV
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