Indium(III) iodide-mediated Strecker reaction in water: an efficient and environmentally friendly approach for the synthesis of α-aminonitrile via a three-component condensation
Tetrahedron, ISSN: 0040-4020, Vol: 64, Issue: 35, Page: 8159-8163
2008
- 88Citations
- 22Captures
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Article Description
A mild, efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via a three-component condensation of aldehyde, amine and TMSCN in the presence of a catalytic amount of indium(III) iodide in water. The reactions proceeded smoothly at room temperature in water to generate the corresponding products in moderate to excellent yields.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0040402008011472; http://dx.doi.org/10.1016/j.tet.2008.06.047; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=47049127635&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S0040402008011472; https://dx.doi.org/10.1016/j.tet.2008.06.047
Elsevier BV
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