An atom-economic synthesis of functionalized pyrroles via a sequential metal-catalyzed three-component reaction
Tetrahedron, ISSN: 0040-4020, Vol: 70, Issue: 14, Page: 2472-2477
2014
- 27Citations
- 7Captures
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Article Description
A three-component reaction of one molecule of imine and two molecules of alkynoates is realized with the catalysis of Cu(I)–Fe(III) in a sequential manner to allow the direct synthesis of functionalized pyrroles, during which, one C–N bond and two C–C bonds are formed with high atom economy. This method benefits from easily available starting materials, low-cost catalysts, and convenient operations.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0040402014000799; http://dx.doi.org/10.1016/j.tet.2014.01.037; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84896085826&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S0040402014000799; https://dx.doi.org/10.1016/j.tet.2014.01.037
Elsevier BV
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