A concise and improved synthesis of (+)-eleutherin, (+)-allo-eleutherin and a formal synthesis of (+)-nocardione B
Tetrahedron: Asymmetry, ISSN: 0957-4166, Vol: 22, Issue: 4, Page: 487-492
2011
- 19Citations
- 13Captures
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Article Description
A concise and improved stereoselective synthesis of (+)-eleutherin, (+)-allo-eleutherin and the formal synthesis of (+)-nocardione B is described. The synthesis is based on a Dötz benzannulation and an improved oxa-Pictet–Spengler cyclization as the key steps. The synthesis is achieved in six steps in overall yields of 18% for eleutherin and 20% for allo-eleutherin.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0957416611000796; http://dx.doi.org/10.1016/j.tetasy.2011.02.011; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79953721917&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S0957416611000796; https://dx.doi.org/10.1016/j.tetasy.2011.02.011
Elsevier BV
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