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Chiral terpene auxiliaries IV: new monoterpene PHOX ligands and their application in the catalytic asymmetric transfer hydrogenation of ketones

Tetrahedron: Asymmetry, ISSN: 0957-4166, Vol: 28, Issue: 3, Page: 467-472
2017
  • 5
    Citations
  • 0
    Usage
  • 11
    Captures
  • 0
    Mentions
  • 0
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Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    5
    • Citation Indexes
      5
  • Captures
    11

Article Description

New PHOX ligands, derived in three steps from (1 R,2 S,3 R,5 R )-3-amino-apopinan-2-ol 1 and (1 R,2 R,3 S,5 R )-3-amino-pinan-2-ol 2 were applied as chiral ligands for the formation of ruthenium catalysts. The catalysts were used in asymmetric transfer hydrogenations of prochiral ketones producing the corresponding alcohols in moderate to high yields and enantioselectivity.

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