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NaI-mediated oxidative amidation of benzyl alcohols/aromatic aldehydes to benzamides via electrochemical reaction

Tetrahedron Letters, ISSN: 0040-4039, Vol: 70, Page: 153017
2021
  • 9
    Citations
  • 0
    Usage
  • 14
    Captures
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    Mentions
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Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    9
    • Citation Indexes
      9
  • Captures
    14

Article Description

In this research, we have developed a mild electrochemical process for oxidative amidation of benzyl alcohols/aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorganic synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant.

Bibliographic Details

Tanawat Rerkrachaneekorn; Theeranon Tankam; Mongkol Sukwattanasinitt; Sumrit Wacharasindhu

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Chemistry

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