Building the brain mosaic: an expanded view
Trends in Genetics, ISSN: 0168-9525, Vol: 40, Issue: 9, Page: 747-756
2024
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Review Description
The complexity of the brain is closely tied to its nature as a genetic mosaic, wherein each cell is distinguished by a unique constellation of somatic variants that contribute to functional and phenotypic diversity. Postzygotic variation arising during neurogenesis is recognized as a key contributor to brain mosaicism; however, recent advances have broadened our understanding to include sources of neural genomic diversity that develop throughout the entire lifespan, from embryogenesis through aging. Moving beyond the traditional confines of neurodevelopment, in this review, we delve into the complex mechanisms that enable various origins of brain mosaicism.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0168952524001306; http://dx.doi.org/10.1016/j.tig.2024.05.008; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85195278718&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/38853120; https://linkinghub.elsevier.com/retrieve/pii/S0168952524001306
Elsevier BV
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