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Oxygen therapy for cerebral malaria

Travel Medicine and Infectious Disease, ISSN: 1477-8939, Vol: 9, Issue: 5, Page: 223-230
2011
  • 2
    Citations
  • 0
    Usage
  • 34
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    2
    • Citation Indexes
      2
  • Captures
    34

Article Description

Malaria is an important global health issue, killing nearly one million people worldwide each year. There is a disproportionate disease burden, since 89% of cases are of African origin, and 85% of deaths worldwide occur in children under 5 years of age of age. 1 Cerebral malaria (CM) is the most serious complication of infection. Despite prompt anti-malarial treatment, fatalities remain high – mortality rates while undergoing treatment with Artemisinin or quinine-based therapy reach 15% and 22% respectively. 2 There is, therefore, a need to develop an adjunct therapy to preserve neurological function during the treatment period. Recent experimental research has indicated hyperbaric oxygenation (HBO) to be a rational and effective adjunct therapy. 3 This article examines the current understanding of CM, and the possible benefits provided by HBO therapy.

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