Derivation of rough attenuated variants from smooth virulent Aeromonas hydrophila and their immunogenicity in fish
Vaccine, ISSN: 0264-410X, Vol: 28, Issue: 29, Page: 4626-4631
2010
- 26Citations
- 49Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations26
- Citation Indexes26
- 26
- CrossRef22
- Captures49
- Readers49
- 49
Article Description
Aeromonas hydrophila is a Gram-negative bacteria associated with many disease conditions of aquatic animals. Two rough attenuated variants were derived from two smooth virulent types of this bacterium by continuous passage separately in laboratory over a period of 8 years in brain–heart infusion agar. These variants were checked to be rough lipopolysaccharides (LPS) types and attenuated since they neither produced any disease nor mortality in the injected fishes. The immunogenic potential of these variants remained unaltered as compared to parent smooth types and fish immunized with these variants resisted the infection and mortality upon cross challenge. Because of their intact immunogenic potential and loss of virulence, they may be used as candidates for fish immunization.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0264410X10006146; http://dx.doi.org/10.1016/j.vaccine.2010.04.078; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77953120761&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/20457292; https://linkinghub.elsevier.com/retrieve/pii/S0264410X10006146; https://dx.doi.org/10.1016/j.vaccine.2010.04.078
Elsevier BV
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