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Vaccinia virus strain LC16m8 defective in the B5R gene keeps strong protection comparable to its parental strain Lister in immunodeficient mice

Vaccine, ISSN: 0264-410X, Vol: 33, Issue: 45, Page: 6112-6119
2015
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Article Description

Attenuated vaccinia virus strain, LC16m8, defective in the B5R envelope protein gene, is used as a stockpile smallpox vaccine strain in Japan against bioterrorism: the defect in the B5R gene mainly contributes to its highly attenuated properties.

Bibliographic Details

Yokote, Hiroyuki; Shinmura, Yasuhiko; Kanehara, Tomomi; Maruno, Shinichi; Kuranaga, Masahiko; Matsui, Hajime; Hashizume, So

Elsevier BV

Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Veterinary; Medicine

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