Induced humoral immunity of different types of vaccines against most common variants of SARS-CoV-2 in Egypt prior to Omicron outbreak
Vaccine, ISSN: 0264-410X, Vol: 40, Issue: 32, Page: 4303-4306
2022
- 3Citations
- 18Captures
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Metrics Details
- Citations3
- Citation Indexes3
- CrossRef1
- Captures18
- Readers18
- 18
Article Description
The diversity of SARS-CoV-2 continues to lead to the emergence of new SARS-CoV-2 variants. SARS-CoV-2 antibody assays are crucial in managing the COVID-19 pandemic by determining the neutralizing antibody response. This study aims to investigate vaccine-induced antibodies against most common variants of SARS-CoV-2 in Egypt. Sera samples were collected from vaccinated participants and neutralizing activity against the SARS-CoV-2 variants was determined using microneutralization assay. Our results show that the BNT162b2 (Pfizer-BioNTech), ChAdOx1 nCov-19 (AstraZeneca), and Ad26.COV2.S COVID-19 (Janssen) vaccines elicited neutralizing antibody responses more than the BBIBP-CorV vaccine (Sinopharm) against B.1, C.36.3, and AY.32 (Delta) variants. While vaccines remain highly effective in managing the COVID-19 pandemic, ongoing monitoring of vaccine effectiveness is needed.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0264410X22007344; http://dx.doi.org/10.1016/j.vaccine.2022.05.086; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85131793484&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/35697574; https://linkinghub.elsevier.com/retrieve/pii/S0264410X22007344; https://dx.doi.org/10.1016/j.vaccine.2022.05.086
Elsevier BV
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