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FREE RADICAL SCAVENGERS, CATALASE AND SUPEROXIDE DISMUTASE PROVIDE PROTECTION FROM OXALATE-ASSOCIATED INJURY TO LLC-PK 1 AND MDCK CELLS

The Journal of Urology, ISSN: 0022-5347, Vol: 164, Issue: 1, Page: 224-229
2000
  • 160
    Citations
  • 0
    Usage
  • 22
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    160
    • Citation Indexes
      160
  • Captures
    22

Article Description

Current studies have provided evidence that exposure of renal epithelial cells to oxalate and calcium oxalate crystals induces lipid peroxidation and injures the cells. Since oxidant/antioxidant balance is likely to play a critical role, we determined the effect of antioxidant scavengers on production of free radicals and injury to LLC-PK 1 and MDCK cells from exposure to oxalate (Ox) or Ox + calcium oxalate monohydrate (COM) crystals.

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