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Serine alkaline protease from a newly isolated Bacillus sp. SSR1

Process Biochemistry, ISSN: 1359-5113, Vol: 36, Issue: 8, Page: 781-785
2001
  • 122
    Citations
  • 0
    Usage
  • 57
    Captures
  • 0
    Mentions
  • 3
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    122
    • Citation Indexes
      122
  • Captures
    57
  • Social Media
    3
    • Shares, Likes & Comments
      3
      • Facebook
        3

Article Description

An extracellular serine alkaline protease produced by Bacillus sp. SSR1 was purified to homogeneity by Sephadex A-50 and Sepharose 6B column chromatography. The enzyme is a monomeric protein with a molecular weight of 29 and 35 kDa as estimated by SDS–PAGE and native PAGE respectively. The purified enzyme is stable in the alkaline pH range (8.0–11.0) and retains 100% activity at its optimum temperature of 40°C even after 300 min of incubation. The presence of CaCl 2 shifts the optimum temperature to 45°C and produces a 1.3-fold increase in its activity. The enzyme remains active and stable in various detergents and is strongly activated by metal ions (Fe 3+, Ca 2+, Na + )

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