Lymphatic lipid transport is not impaired in ageing rat intestine
Mechanisms of Ageing and Development, ISSN: 0047-6374, Vol: 113, Issue: 3, Page: 219-225
2000
- 2Citations
- 12Captures
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Article Description
Lymphatic lipid transport in the intestine of adult and ageing rats was compared. Adult (8–10 months old) and old (24–26 months old) male Wistar rats were cannulated into the mesenteric lymph under ethrane anesthesia. On the following day, lipid emulsion containing 35.4 mg/h of olive oil was infused intraduodenally for 7 h and lymph collected hourly was assayed for triglyceride and apolipoprotein A-IV (apo A-IV). The results showed there was no difference in lymphatic lipid and apo A-IV transport between adult and old rats. Since apo A-IV synthesis in the enterocytes is linked to the intracellular assembly of lipoprotein, it is likely that in addition to lymphatic transport, production of chylomicrons is not impaired in ageing rats.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0047637499001104; http://dx.doi.org/10.1016/s0047-6374(99)00110-4; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033984776&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10714940; https://linkinghub.elsevier.com/retrieve/pii/S0047637499001104; http://linkinghub.elsevier.com/retrieve/pii/S0047637499001104; http://api.elsevier.com/content/article/PII:S0047637499001104?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0047637499001104?httpAccept=text/plain; http://dx.doi.org/10.1016/s0047-6374%2899%2900110-4; https://dx.doi.org/10.1016/s0047-6374%2899%2900110-4
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