Membrane infrastructure in Urinary Tubules
International Review of Cytology, ISSN: 0074-7696, Vol: 73, Issue: C, Page: 183-242
1981
- 58Citations
- 1Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations58
- Citation Indexes58
- 58
- CrossRef49
- Captures1
- Readers1
Article Description
This chapter describes the freeze-fracture ultrastructure of the plasma membrane of epithelial cells at the level of the glomerulus, proximal tubule, loop of Henle, distal tubule, and collecting duct. The chapter provides a qualitative description of the membrane faces and junctional differentiations. A quantitative analysis of the number and size of intramembrane particles representing protein-containing structures in the membrane is also provided. Freeze-fracturing involves freezing a tissue specimen at a low temperature of -150°C, fracturing the frozen specimen with a cooled microtome blade, and then shadow-casting the frozen and fractured surface with platinum and carbon. The systematic application of the freeze-fracture technique to the kidney revealed an impressive mosaic of membrane structure among the epithelial cells lining the urinary tubules. There are variations in the density, size, and shape of intramembrane particles among membrane domains of the same cell, among different cells, and in the degree of development of intercellular junctions between cells.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0074769608612899; http://dx.doi.org/10.1016/s0074-7696(08)61289-9; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0019730096&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/7028660; http://linkinghub.elsevier.com/retrieve/pii/S0074769608612899; https://linkinghub.elsevier.com/retrieve/pii/S0074769608612899; http://dx.doi.org/10.1016/s0074-7696%2808%2961289-9; https://dx.doi.org/10.1016/s0074-7696%2808%2961289-9
Elsevier BV
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