A radioimmunoassay determination of the concentrations of prostaglandins E 2 and F 2α in painful and asymptomatic human dental pulps
Journal of Endodontics, ISSN: 0099-2399, Vol: 11, Issue: 8, Page: 330-335
1985
- 81Citations
- 23Captures
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Metrics Details
- Citations81
- Citation Indexes81
- 81
- CrossRef76
- Captures23
- Readers23
- 23
Article Description
The purpose of this study was to determine the concentrations of prostaglandin E 2 and prostaglandin F 2α in painful and asymptomatic human dental pulps. Pulps were obtained from three groups of teeth: uninflamed pulps, asymptomatic teeth with caries and/or large restorations, and symptomatic teeth with the clinical diagnosis of irreversible pulpitis. Pulps were dissected from the teeth and stored in liquid nitrogen. They were homogenized in 40% ethanol and a lipid solvent extraction was performed. Prostaglandin levels were measured using radioimmunoassay. The pulps which were likely to demonstrate inflammation had significantly higher mean concentrations of prostaglandin E 2 than did the uninflamed pulps (p<0.05). Painful pulps had a much higher level of both prostaglandin E 2 and prostaglandin F 2α than the asymptomatic pulps (p < 0.01).
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S009923998580039X; http://dx.doi.org/10.1016/s0099-2399(85)80039-x; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0022105938&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/3863874; https://linkinghub.elsevier.com/retrieve/pii/S009923998580039X; http://linkinghub.elsevier.com/retrieve/pii/S009923998580039X; http://api.elsevier.com/content/article/PII:S009923998580039X?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S009923998580039X?httpAccept=text/plain; http://dx.doi.org/10.1016/s0099-2399%2885%2980039-x; https://dx.doi.org/10.1016/s0099-2399%2885%2980039-x
Elsevier BV
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