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Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial

The Lancet, ISSN: 0140-6736, Vol: 379, Issue: 9826, Page: 1613-1620
2012
  • 535
    Citations
  • 0
    Usage
  • 355
    Captures
  • 5
    Mentions
  • 46
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    535
    • Citation Indexes
      522
    • Policy Citations
      10
      • Policy Citation
        10
    • Clinical Citations
      3
      • PubMed Guidelines
        3
  • Captures
    355
  • Mentions
    5
    • References
      3
      • Wikipedia
        3
    • Blog Mentions
      1
      • Blog
        1
    • News Mentions
      1
      • News
        1
  • Social Media
    46
    • Shares, Likes & Comments
      46
      • Facebook
        46

Most Recent News

Early corticosteroid therapy associated with better outcomes in Kawasaki Disease

1. In this meta-analysis of available comparative studies, use of corticosteroids as adjunctive therapy to IVIG and aspirin in Kawasaki disease was associated with a lower risk of coronary artery abnormality and earlier defervescence compared to IVIG/ASA alone. 2. In subgroup analysis the earlier timing of steroid therapy had lower risk of coronary artery abnormality

Article Description

Evidence indicates that corticosteroid therapy might be beneficial for the primary treatment of severe Kawasaki disease. We assessed whether addition of prednisolone to intravenous immunoglobulin with aspirin would reduce the incidence of coronary artery abnormalities in patients with severe Kawasaki disease.

Bibliographic Details

Kobayashi, Tohru; Saji, Tsutomu; Otani, Tetsuya; Takeuchi, Kazuo; Nakamura, Tetsuya; Arakawa, Hirokazu; Kato, Taichi; Hara, Toshiro; Hamaoka, Kenji; Ogawa, Shunichi; Miura, Masaru; Nomura, Yuichi; Fuse, Shigeto; Ichida, Fukiko; Seki, Mitsuru; Fukazawa, Ryuji; Ogawa, Chitose; Furuno, Kenji; Tokunaga, Hirohide; Takatsuki, Shinichi; Hara, Shinya; Morikawa, Akihiro; RAISE study group investigators

Elsevier BV

Medicine

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