Intrathecal IgG synthesis and autoantibody-secreting cells in multiple sclerosis
Journal of Neuroimmunology, ISSN: 0165-5728, Vol: 108, Issue: 1, Page: 207-215
2000
- 37Citations
- 16Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations37
- Citation Indexes37
- 37
- CrossRef31
- Captures16
- Readers16
- 16
Article Description
We studied intrathecal IgG synthesis and autoantibody-secreting cells in 148 patients with possible onset symptoms of MS (POSMS) or clinically definite MS (CDMS). In POSMS intrathecal synthesis of IgG oligoclonal bands and abnormalities on T2-weighted magnetic resonance imaging were associated but the former were more prevalent. The cerebrospinal fluid (CSF) leukocyte count and the number of anti-protelipid protein antibody-secreting cells in cerebrospinal fluid (CSF) correlated with disease activity in POSMS. Intrathecal IgG synthesis levels and the number of anti-myelin basic protein antibody-secreting cells in CSF correlated with disease activity in CDMS. Our results support recent reports of pathogenetic heterogeneity and a pathogenetic role of the antibody response in MS.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0165572800002927; http://dx.doi.org/10.1016/s0165-5728(00)00292-7; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034255925&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10900355; https://linkinghub.elsevier.com/retrieve/pii/S0165572800002927; http://linkinghub.elsevier.com/retrieve/pii/S0165572800002927; http://api.elsevier.com/content/article/PII:S0165572800002927?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0165572800002927?httpAccept=text/plain; http://dx.doi.org/10.1016/s0165-5728%2800%2900292-7; https://dx.doi.org/10.1016/s0165-5728%2800%2900292-7
Elsevier BV
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