Recent advances in liposome technologies and their applications for systemic gene delivery
Advanced Drug Delivery Reviews, ISSN: 0169-409X, Vol: 30, Issue: 1, Page: 73-83
1998
- 118Citations
- 79Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations118
- Citation Indexes118
- 118
- CrossRef87
- Captures79
- Readers79
- 64
- 15
Review Description
The recent clinical successes experienced by liposomal drug delivery systems stem from the ability to produce well-defined liposomes that can be composed of a wide variety of lipids, have high drug-trapping efficiencies and have a narrow size distribution, averaging less than 100 nm in diameter. Agents that prolong the circulation lifetime of liposomes, enhance the delivery of liposomal drugs to specific target cells, or enhance the ability of liposomes to deliver drugs intracellularly can be incorporated to further increase the therapeutic activity. The physical and chemical requirements for optimum liposome drug delivery systems will likely apply to lipid-based gene delivery systems. As a result, the development of liposomal delivery systems for systemic gene delivery should follow similar strategies.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0169409X97001087; http://dx.doi.org/10.1016/s0169-409x(97)00108-7; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032473563&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10837603; http://linkinghub.elsevier.com/retrieve/pii/S0169409X97001087; http://api.elsevier.com/content/article/PII:S0169409X97001087?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0169409X97001087?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/S0169409X97001087; http://dx.doi.org/10.1016/s0169-409x%2897%2900108-7; https://dx.doi.org/10.1016/s0169-409x%2897%2900108-7
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