The physiology of corticotropin-releasing hormone deficiency in mice
Peptides, ISSN: 0196-9781, Vol: 22, Issue: 5, Page: 725-731
2001
- 47Citations
- 38Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations47
- Citation Indexes47
- 47
- CrossRef40
- Captures38
- Readers38
- 38
Article Description
A review of the generation and characterization of corticotropin-releasing hormone (CRH)-deficient mice is presented. The studies summarized demonstrate the central role of CRH in the pituitary-adrenal axis response to stress, circadian stimulation, and glucocorticoid withdrawal. Additionally, pro-inflammatory actions of CRH at sites of local inflammation are given further support. In contrast, behavioral effects during stress that had been ascribed to CRH action are not altered in CRH-deficient mice. The normal behavioral response to stress in CRH-deficient mice strongly suggests the importance of other, possibly as yet undiscovered, CRH-like molecules.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0196978101003850; http://dx.doi.org/10.1016/s0196-9781(01)00385-0; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035038461&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/11337085; https://linkinghub.elsevier.com/retrieve/pii/S0196978101003850; http://linkinghub.elsevier.com/retrieve/pii/S0196978101003850; http://api.elsevier.com/content/article/PII:S0196978101003850?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0196978101003850?httpAccept=text/plain; http://dx.doi.org/10.1016/s0196-9781%2801%2900385-0; https://dx.doi.org/10.1016/s0196-9781%2801%2900385-0
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