Kinetic and pharmacological analysis of l -[ 35 S]cystine transport into rat brain synaptosomes
Neurochemistry International, ISSN: 0197-0186, Vol: 36, Issue: 6, Page: 513-521
2000
- 28Citations
- 10Captures
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Metrics Details
- Citations28
- Citation Indexes28
- 28
- CrossRef26
- Captures10
- Readers10
- 10
Article Description
The synaptosomal transport of l -[ 35 S]cystine occurs by three mechanisms that are distinguishable on the basis of their ionic dependence, kinetics of transport and the specificity of inhibitors. They are (a) low affinity sodium-dependent transport ( K m 463±86 μM, V max 185±20 nmol mg protein −1 min −1 ), (b) high affinity sodium-independent transport ( K m 6.90±2.1 μM, V max 0.485±0.060 nmol mg protein −1 min −1 ) and (c) low affinity sodium-independent transport ( K m 327±29 μM, V max 4.18±0.25 nmol mg protein −1 min −1 ).
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0197018699001515; http://dx.doi.org/10.1016/s0197-0186(99)00151-5; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0033982706&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10762088; https://linkinghub.elsevier.com/retrieve/pii/S0197018699001515; http://linkinghub.elsevier.com/retrieve/pii/S0197018699001515; http://api.elsevier.com/content/article/PII:S0197018699001515?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0197018699001515?httpAccept=text/plain; http://dx.doi.org/10.1016/s0197-0186%2899%2900151-5; https://dx.doi.org/10.1016/s0197-0186%2899%2900151-5
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