Effects of noise on the off rate of Ca 2+ binding proteins in a coupled biochemical cell system
Biophysical Chemistry, ISSN: 0301-4622, Vol: 94, Issue: 3, Page: 201-207
2001
- 17Citations
- 3Captures
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Article Description
We investigated numerically the kinetic properties of calcium binding proteins by using a three-calcium store model and discussed the response of a two-way coupled biochemical cell system, whose subsystems were coupled via diffusion-like cytosolic calcium transfer through gap junctions, to the external stimulation. When we used noise to modulate the off rate of the Ca 2+ binding proteins in simulation, an SR-like phenomenon of synchronous oscillations is observed. In addition, the interaction involving noise, coupling and the dynamics of Ca 2+ binding proteins is discussed.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0301462201002332; http://dx.doi.org/10.1016/s0301-4622(01)00233-2; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035951162&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/11804730; http://linkinghub.elsevier.com/retrieve/pii/S0301462201002332; http://api.elsevier.com/content/article/PII:S0301462201002332?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0301462201002332?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/S0301462201002332; http://dx.doi.org/10.1016/s0301-4622%2801%2900233-2; https://dx.doi.org/10.1016/s0301-4622%2801%2900233-2
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