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Quantitation by HPLC of Amines as Dansyl Derivatives

Journal of Chromatography Library, ISSN: 0301-4770, Vol: 70, Issue: C, Page: 445-470
2005
  • 7
    Citations
  • 0
    Usage
  • 21
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    7
    • Citation Indexes
      7
  • Captures
    21

Article Description

The potential of dansyl chloride as labelling reagent for the derivatization of amines prior their determination by high performance liquid chromatography is overviewed. Different approaches for carrying out the dansylation reaction, such as bath derivatization, the use of solid supports and automated on-line procedures are discussed. Dansylation, separation and detection of low-molecular-mass aliphatic amines, biogenic amines including polyamines and aromatic amines of clinical significance are summarized. From a critical study, the most favourable conditions for the determination of these amine compounds in real samples such as waters, foods, beverages and clinical samples are reported.

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