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Influence of dietary selenium supplementation and exercise on thiol-containing enzymes in mice

Nutrition, ISSN: 0899-9007, Vol: 19, Issue: 7, Page: 627-632
2003
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Article Description

Exercise markedly increases oxygen uptake by active muscles and consequently increases generation of reactive oxygen species. A dietary deficiency in selenium (Se) can increase the sensitivity of the living system to oxidative stress. δ-Aminolevulinate dehydratase (δ-ALA-D), succinate dehydrogenase (SDH), and lactate dehydrogenase (LDH) are sulfhydryl-containing enzymes, and their activities are sensitive to the presence of oxidizing agents. We investigated the effect of Se deficiency and supplementation on δ-ALA-D, SDH, and LDH activities in mice subjected to swim training for 8 wk.

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