Ultrastructural Immunolocalization of Osteopontin in Metaphyseal and Cortical Bone
Matrix, ISSN: 0934-8832, Vol: 11, Issue: 3, Page: 206-213
1991
- 78Citations
- 11Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations78
- Citation Indexes78
- 78
- CrossRef67
- Captures11
- Readers11
- 11
Article Description
The ultrastructural localization of osteopontin in bone was determined especially focussing on the relationship to bone forming cells, i. e. osteoblasts and osteocytes. Thus, rat metaphyseal and cortical bone was fixed in a mixture of low concentration glutar- and paraformaldehyde and embedded at low temperature in Lowicryl K11M. Polyclonal antibodies raised against rat osteopontin fusion protein were incubated on ultrathin sections and protein G coated with 5-nm colloidal gold was used for detection. The results demonstrate most intensive labeling in the mineralization front of newly formed bone; whereas lower concentration of label was found in the osteoid both in metaphyseal and cortical bone. The concentration of marker was substantially higher in newly formed bone near osteoblasts compared to bone constituting the osteocyte lacuna. lntracellularly the prevailing localization of label was to large Golgi vesicles in osteoblasts. Only focally local accumulation of marker was seen at the cell/osteoid surface. The observations suggest a function of osteopontin also in the mineral turnover of newly formed bone.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0934883211801605; http://dx.doi.org/10.1016/s0934-8832(11)80160-5; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0025844764&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/1870452; http://linkinghub.elsevier.com/retrieve/pii/S0934883211801605; http://api.elsevier.com/content/article/PII:S0934883211801605?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0934883211801605?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/S0934883211801605; http://dx.doi.org/10.1016/s0934-8832%2811%2980160-5; https://dx.doi.org/10.1016/s0934-8832%2811%2980160-5
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know