K- ras mutations in colorectal adenocarcinomas and neighbouring transitional mucosa
European Journal of Cancer, ISSN: 0959-8049, Vol: 34, Issue: 13, Page: 2053-2057
1998
- 19Citations
- 13Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations19
- Citation Indexes19
- 19
- CrossRef15
- Captures13
- Readers13
- 13
Article Description
The K- ras gene in codons 12 and 13 was investigated using allele-specific polymerase chain reaction in matched normal mucosa ( n =106), transitional mucosa ( n =69) and tumours ( n =149) from 149 patients with colorectal adenocarcinomas. K- ras mutations in codon 12 were detected in 41/149 (28%) of tumours and 4/69 (6%) of transitional mucosa samples, but not in the normal mucosa. Further, mutation rates were increased in younger patients ( P =0.001) and in mucinous carcinomas (50%) compared with well differentiated (17%), moderately differentiated (26%) or poorly differentiated (24%) tumours. Our findings indicate that mucinous carcinoma may represent a distinct genetic entity.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0959804998002834; http://dx.doi.org/10.1016/s0959-8049(98)00283-4; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032401026&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10070310; https://linkinghub.elsevier.com/retrieve/pii/S0959804998002834; http://linkinghub.elsevier.com/retrieve/pii/S0959804998002834; http://api.elsevier.com/content/article/PII:S0959804998002834?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0959804998002834?httpAccept=text/plain; http://dx.doi.org/10.1016/s0959-8049%2898%2900283-4; https://dx.doi.org/10.1016/s0959-8049%2898%2900283-4
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