Kinase bypass: A new strategy for anti-HIV drug design
Bioorganic & Medicinal Chemistry Letters, ISSN: 0960-894X, Vol: 3, Issue: 6, Page: 1207-1210
1993
- 24Citations
- 4Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
The 5′-bis(trichloroethyl) phosphate derivatives of several 3′-O-acyl thymidines were prepared from the thymidine phosphate. Even though the parent nucleosides are inactive as antiviral agents, the phosphates are selective inhibitors of the proliferation of HIV. This activity is attributed to a new mechanism of action, we herein describe as “kinase by-pass”.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0960894X00803169; http://dx.doi.org/10.1016/s0960-894x(00)80316-9; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027262964&origin=inward; http://linkinghub.elsevier.com/retrieve/pii/S0960894X00803169; http://api.elsevier.com/content/article/PII:S0960894X00803169?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0960894X00803169?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/S0960894X00803169; https://api.elsevier.com/content/article/PII:S0960894X00803169?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S0960894X00803169?httpAccept=text/plain; http://dx.doi.org/10.1016/s0960-894x%2800%2980316-9; https://dx.doi.org/10.1016/s0960-894x%2800%2980316-9
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