Chapter 10 The Interaction of Mitochondrial Membranes with Reactive Oxygen and Nitrogen Species
Current Topics in Membranes, ISSN: 1063-5823, Vol: 61, Page: 211-242
2008
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- 10Captures
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Review Description
Within the context of the overall effects of free radicals (ROS and RNS) on biological membranes, the mitochondrion offers a unique biochemical environment which leads to a number of organelle-specific reactions, This includes a unique complement of membrane lipids and proteins, an alkaline pH in the matrix, specialized systems for the generation and quenching of ROS and RNS, and a tightly controlled redox status. All of these parameters come together in a highly orchestrated system that is essential to the proper functioning of the mitochondrion. This chapter will examine some of the mitochondria-specific aspects of ROS and RNS reactions with membranes, within the context of the many disease processes that originate at the organelle level.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S106358230800210X; http://dx.doi.org/10.1016/s1063-5823(08)00210-x; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=48649087184&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S106358230800210X; http://linkinghub.elsevier.com/retrieve/pii/S106358230800210X; http://dx.doi.org/10.1016/s1063-5823%2808%2900210-x; https://dx.doi.org/10.1016/s1063-5823%2808%2900210-x
Elsevier BV
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