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A Brief Review of Computational Gene Prediction Methods

Genomics, Proteomics & Bioinformatics, ISSN: 1672-0229, Vol: 2, Issue: 4, Page: 216-221
2004
  • 70
    Citations
  • 0
    Usage
  • 373
    Captures
  • 1
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    70
  • Captures
    373
  • Mentions
    1
    • References
      1
      • Wikipedia
        1
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Review Description

With the development of genome sequencing for many organisms, more and more raw sequences need to be annotated. Gene prediction by computational methods for finding the location of protein coding regions is one of the essential issues in bioinformatics. Two classes of methods are generally adopted: similarity based searches and ab initio prediction. Here, we review the development of gene prediction methods, summarize the measures for evaluating predictor quality, highlight open problems in this area, and discuss future research directions.

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