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Aromatic Polyketides from the Mangrove-Derived Streptomyces sp. SCSIO 40069

Journal of Natural Products, ISSN: 1520-6025, Vol: 86, Issue: 4, Page: 979-985
2023
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Article Description

A chemical investigation of Streptomyces sp. SCSIO 40069 resulted in the isolation of a series of aromatic polyketides with rare skeletons, including five new compounds RM18c-RM18g (1-5) and three known ones (6-8). Their structures and absolute configurations were determined by diverse methods, including HRMS and NMR spectra, chemical reaction, Snatzke’s method, quantum mechanical-nuclear magnetic resonance (QM-NMR), and X-ray crystallographic analysis. Compounds 1, 2, 4b, and 8 displayed moderate or weak antibacterial activities.

Bibliographic Details

Sun, Lili; Zhu, Hanning; Zhang, Liping; Zhu, Yiguang; Ratnasekera, Disna; Zhang, Changsheng; Zhang, Qingbo

American Chemical Society (ACS)

Chemistry; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics; Medicine

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