PlumX Metrics
Embed PlumX Metrics

Acyclic aminocarbenes in catalysis

ACS Catalysis, ISSN: 2155-5435, Vol: 2, Issue: 8, Page: 1802-1816
2012
  • 155
    Citations
  • 0
    Usage
  • 66
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    155
    • Citation Indexes
      155
  • Captures
    66

Review Description

Acyclic aminocarbenes have received much less attention as ancillary ligands in homogeneous catalysis compared with their cyclic relatives (i.e., N-heterocyclic carbenes, NHCs), despite having a longer history and greater structural variety. Although these species are generally more fragile than NHCs, recent advances in the synthesis and catalytic application of metal complexes of acyclic carbenes have brought increased attention to these underutilized ligands. It is increasingly clear that acyclic carbenes possess unique properties that distinguish them from other ligand classes and make them potentially valuable for catalysis. These include exceptional donor ability, conformational flexibility, and wide N-C(carbene)-N angles that can place bulky or chiral substituents near catalytic substrate binding sites. This purpose of this Perspective is to review and critically assess recent progress in this forefront area of catalyst design. Syntheses and ligand properties of acyclic diaminocarbenes, aminooxycarbenes, and other aminocarbenes are reviewed with a view toward catalytic relevance. A special focus is to highlight catalytic reactions in which acyclic carbene ligands confer unusual selectivity or activity on metal catalysts compared with conventional ligand types. Particularly promising catalytic results have been obtained with acyclic carbene complexes of gold, including some highly enantioselective catalytic transformations. © 2012 American Chemical Society.

Bibliographic Details

Legrande M. Slaughter

American Chemical Society (ACS)

Chemical Engineering; Chemistry

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know