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Enzymatic lithography of phospholipid bilayer films by stereoselective hydrolysis

Journal of the American Chemical Society, ISSN: 0002-7863, Vol: 127, Issue: 18, Page: 6546-6547
2005
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Article Description

The stereoselective phospholipase A-catalyzed hydrolysis of patterned phospholipid bilayers consisting of the l- and d-isomers of α-dilauroylphosphatidylcholine (DLPC) and α-dipalmitoylphosphatidylcholine (DPPC) is reported. The stereochemically directed enzyme lithography demonstrated herein allows the parallel modification of large surface areas and constitutes a potentially useful method to structure biomimetic films, given the stereospecific action of many enzymes. Copyright © 2005 American Chemical Society.

Bibliographic Details

Moraille, Patricia; Badia, Antonella

American Chemical Society (ACS)

Chemical Engineering; Chemistry; Biochemistry, Genetics and Molecular Biology

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